Ecstacy

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neurochemical markers and mdma neurotoxicity
MDMA in somewhat high doses has been shown to be a neurotoxin in experimental animals. The applicability of these results to human use, however, still remains unclear.

Subjective Reports of the Effects of MDMA in a Clinical Setting
The psychological effects of MDMA were first reported in 1978 by Shulgin and Nichols (Shulgin & Nichols, 1978). Because it had originally been patented in Germany in 1914 and was no longer patentable, no pharmaceutical manufacturer could be found who was interested in sponsoring an Investigational New Drug Application with the Food and Drug Administration or in supporting research (Shulgin, 1980). In 1980, it was learned that, in California at least, drugs that were not yet available commercially could be used within a physician's practice if they were manufactured by the physician or by a pharmacist (Younger, 1978). The State medical board recommended that there be peer review, informed consent and supporting scientific literature when conducting experimental work (California Board of Medical Quality Assurance, 1980). This article is a summary report of data gathered from the first 29 people administered MDMA in a clinical setting.

MDMA
MDMA from the Vaults of Erewid. Erowid is a small not for profit organization dedicated to studying and providing information about humanity's never-ending search for meaning and spirit. We recognize that every individual is on their own path and that no single path is best, or even functional, for all. History shows us that regardless of social or legal controls, people will follow their own individual paths in this search for meaning. It is extremely important for information to be freely available about different techniques, practices, methods, and lifestyles, whether traditional or unconventional.